Primary intracranial malignant ectomesenchymoma in pineal region: a rare case report and review of literature

Primary intracranial malignant ectomesenchymoma (MEM) is a rare proliferative disorder that only occasionally involves the central nervous system. We presented a 16-year-old case of primary MEM located in pineal region. The patient was treated by total surgical resection followed by radiation and experienced no recurrence during the 6-month follow-up. The clinicopathological features of this case raised two points for the first record, as the first regarded the special age and pineal location as well as the second regarded the specific pathological components with malignant large round cells. The diagnosis for MEM is still challenging. The histological displays, immunophenotypical characteristics and cytogenesis arrays are still reliable evidence for diagnosis. Surgical resection has been demonstrated an effective treatment, but radiotherapy and chemotherapy have not been confirmed reliable therapeutic efficiency.